OTUD5 (NM_001136158) Human 3' UTR Clone

Specifications

Product Data
Product Name	OTUD5 (NM_001136158) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DUBA; MCAND
ACCN	NM_001136158
Insert Size	954 bp
Sequence Data	Insert Sequence (showhide) >SC211245 3’UTR clone of NM_001136158 The sequence shown below is from the reference sequence of NM_001136158. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CACAGAGACCCGCCCCCAGACAAGAGTTGATGGAGACCCAGGGATTGGACACCATCTCCCAACCCCAGG GACTCGGGCAAGGGTGCCGAAGATAGACAAGAGGCACACAGAGACAGACCAACTGGCAGCCAGGCAGCC CCAGAGGAGAGAGACATTCAGACAGAGGAAAGTCTCCCTGCCCCTCATTCCTTCCAAGATGAGAAAAAC TTGCCGCCACCCCCCGACACTGATGCCAGGGAGGTGGGAGGAAGAAGTGGGAAATTTCCCTTCCCAGTA CCCCCAAGAACGTCTGAGCCTTCAATGTTGAATTTTTTCTTTATTAAAATTACTTTTATCTTATAAAAT CAACTAATCAAAAATGATATAGACGACAGCACTGGCTCTGTGAAGGTGGCATCTTTCTGGGCAGGCAGG CCATGGGGCATGGAGGAGGGTGCAAAGATATGGGTTGCTGTCTTCTGGCCTCCAGCTGCATGGAGGCCG GCCCAGGGTCTAGGGTGTGCACTGGGCAAGGGCAGGGCGGCAGGTGTCAGGCCGGCTTGGACAATGAAA CCCTGACCTTGCTGCATTCCTTTTGCTTCCACCACCACTAGCTTCTTTGGAATCTTGGGGTGGGGGTCA TCTTTGGGGATTATGGCTGCCACCCGGGATTTGAGTGTAGGGAGTGTGGGAGCAGCCTTGGCAGATGGG GCACCCGTGCCCTGCAGGTGTTGACAAGATCCGCCATCTGTAATGTCCTTGGCACAATAAAACCAAATG TCAGTTTCCCTGAGCGACTCTGTTCTGTGTGGGGCAGGGGTTGGGCGGGCCTCTGGGCAGAGGATGCAA TGGCACGGACCTTGGCTTGACCTCAGAGGTGTGAATGCTCTCCAGCAGGGTCTGTCTGGGGGCCTGGAG TTTGTATTTGATTTGCTGCTTATTAAACCTCCTTCTGGACCTATTGCCACTGGAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001136158.2
Synonyms	DUBA; MCAND
Summary	This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Oct 2008]
Locus ID	55593
MW	34.2

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