SHFM3 (FBXW4) (NM_022039) Human 3' UTR Clone

Specifications

Product Data
Product Name	SHFM3 (FBXW4) (NM_022039) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DAC; FBW4; FBWD4; SHFM3; SHSF3
ACCN	NM_022039
Insert Size	655 bp
Sequence Data	Insert Sequence (showhide) >SC209238 3’UTR clone of NM_022039 The sequence shown below is from the reference sequence of NM_022039. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCCACGTCCTGGATTTTCAAAACCCATGACCGTCAGGGCCACCCCTGCCTCTGGGCCAGGGAAACCAG CTACTCAGGGACTTCTCTTGCCTGGAGGGTGCAGTGATAGCTCCTCCTCACTGCCCCACTGTGCTCCTG GGCCTGTGACCCCAGTGCTCAGGCACCTTGCACTAGAGGCTTCTGACTCCTGGGACTTTGGAGCTTACC AGAGATGCAGTCCCTCCCAGGAACCTGTTGGAGAGGCAGGACCTGCTGCTTTAGAGTGCGGCTGAACCC GGGCCTTGCGTCCCTGTTTGGCCAGAGCAAGGATCTGGCCTGGAGAGGCCCATCCTATACCCCTTATTA GAGCCATGACAGCCTACAGAGTGAGGTGAGGTGCTCCCACCTTCCCAGATGGTTCCTTTCTGCCCCTTC CTGGAAGGAAAGGTGAGGCTGCCAATAGCCTCCTGGCACCAGCCAGACCTCACCCTTGACCAACCTCTC GGGGCTGGGGGTTCATTCCTGGGGCACTGTGGCCTGGTTTTGCTTTGAAACCAAGAAAGAGCAAAGGGA ACCCAGCAGTTCTGAGTGAGTTCTGAGCCAGCCCTACCTCAGGCTGGCTGTTGAGACATGCTACAATTT TCATTTTTGTAAAAATAAAGCTTGATTGTTCACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_022039.4
Synonyms	DAC; FBW4; FBWD4; SHFM3; SHSF3
Summary	This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22. [provided by RefSeq, Jul 2008]
Locus ID	6468
MW	23.6

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.