Mortality Factor 4 like 2 (MORF4L2) (NM_001142431) Human 3' UTR Clone

Specifications

Product Data
Product Name	Mortality Factor 4 like 2 (MORF4L2) (NM_001142431) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MORFL2; MRGX
ACCN	NM_001142431
Insert Size	693 bp
Sequence Data	Insert Sequence (showhide) >SC208791 3’UTR clone of NM_001142431 The sequence shown below is from the reference sequence of NM_001142431. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCTGCTGAGTACCACCGCAAAGCCCTGTGAGCGTCTACAGACAGCTCACCATTTTTGTCCTGTATCTGT AAACACTTTTTGTTCTTAGTCTTTTTCTTGTAAAATTGATGTTCTTTAAAATCGTTAATGTATAACAGG GCTTATGTTTCAGTTTGTTTTCCGTTCTGTTTTAAACAGAAAATAAAAGGAGTGTAAGCTCCTTTTCTC ATTTCAAAGTTGCTACCAGTGTATGCAGTAATTAGAACAAAGAAGAAACATTCAGTAGAACATTTTATT GCCTAGTTGACAACATTGCTTGAATGCTGGTGGTTCCTATCCCTTTGACACTACACAATTTTCTAATAT GTGTTAATGCTATGTGACAAAACGCCCTGATTCCTAGTGCCAAAGGTTCAACTTAATGTATATACCTGA AAACCCATGCATTTGTGCTCTTTTTTTTTTTTTATGGTGCTTGAAGTAAAACAGCCCATCCTCTGCAAG TCCATCTATGTTGTTCTTAGGCATTCTATCTTTGCTCAAATTGTTGAAGGATGGTGATTTGTTTCATGG TTTTTGTATTTGAGTCTAATGCACGTTCTAACATGATAGAGGCAATGCATTATTGTGTAGCCACGGTTT TCTGGAAAAGTTGATATTTTAGGAATTGTATTTCAGATCTTAAATAAAATTTGTTTCTAAATTTCAAAG CAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001142431.2
Synonyms	MORFL2; MRGX
Summary	Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.[UniProtKB/Swiss-Prot Function]
Locus ID	9643
MW	27.1

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