SPTBN2 (NM_006946) Human 3' UTR Clone

Specifications

Product Data
Product Name	SPTBN2 (NM_006946) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GTRAP41; SCA5; SCAR14
ACCN	NM_006946
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC208378 3’UTR clone of NM_006946 The sequence shown below is from the reference sequence of NM_006946. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGCTTCAGCTTCTTTAAGAAGAACAAGTAGTTGGGGGCAAGGTCCCAGGCCAACTCCCTCCCTCCGTTC AGGAAACTGCCAGGGACAGTCGACAGGGACCGCCCTCTTGTCAGGACAACTGCCTGCTGCTAGGGTCTG TTGCCAAGGTCAACCCATCACCAGGAACTGTCACTGGGGACGAGTCCATGTTCCCAAGGGCAGCCCTTC TCTTCTGCTGTTTAATTCCAGACTGGTGGTGGGACCCAGGTAACCCCCTCTCCCACCCCCGCCGACTTC TCCCCTTTCCCCAGCCTCGTGCCTCTGTCCCTCACCACGGTGTGGACAGTGCCGCACCCTCAACATAGG CCATGTGGGGAGTGGCTGCCCCTGCCTCAGGGTCATTCTCCTGCCATGCGAGGGCACTCGCCTTCTGCC TTCTGGTTCCTCACCCCTCAGACCAGCCAGGAACCTCTCAGAGCTGAAGCAGGCCCTGGGGGCAGAAGT GCCAGATGACAGTCAGAGGCGCAGGAGCCCTCCCTCCCCACCCCCACCCTGTAACTCCAGCTGCCACTC CATCTCCAGCTGCTCTCAATGGCTTCCAGGTGTGTTGTTCGGGGACAGCCACCGCCTTGAGTCTGGCCA AGGAGGTGATTAAACAGCTCAGCTTCTCTCACCGCCTCTGGGTGTCTTTGCTTTCCTGACCACAGCCTC TCTGCCCAAGCCTGTGTCCTCTCCTTCCGTTCTGGTCTCCTTCATCTCACGTTTCCCCAGCCTCCAAGC TCTTGAAGAGCCGTGTCACACTGAGAGCTTCCCTGACCTGGTCTCATTTCCCTCTGACAGTGACCTCCA GTGTGCTGGGTTGACCAATGCCAAGCCTCTTTTTAAACCAAAGTAGTTCACCATGGGTTGGGATGATGT CAACAAGCAGTATTCATGTTAAAAAGCAATGAGGGACTCCTTCCCTGGTGCACAATTTTCTTCACTTGT GATCTCTAAACTGTTTTCAAATTGGAAGACTGGGAAGCATTGCTACAGCCCCAGCCAGTCTCAGCCACT GCTCAGCCCAGTGGTGGAAAGCTGAGCACACAGCGGGTGCTTACTGCCCCCACTTGCCGTCTGCTCTCC AGTAGATCAAGGGACCTCAGACAGGGATCTGAGAAGTGGCAGGTTCCAATAAACTGATCAACAGAATGA AGTCACTCTGGGAAGCCATGAGGTGACTTTACAGCCCAAGCATGTAAATATACACACAGAGGATAATAT ATATTCTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTCTGTCAGCCAAGCTGGACTGCAGTGGCGC AATCACAGCCCATTGCAACCTCCACCTCCTGGGTTCAAGCAATCCTCCCACCTCAGCCTCCCGAGTAGC CTGAACCACAGGCACATGCCATCATACCCGACTAAGTCTGTTTGTTTTTTGTAGAGACGGGGTCTCACT ATGTTGCCCAGGTCGGTCTCGAATTCCTGGGCCCAAGTGATTCTCTCACCTTGGCCTCAAACTGTTGGG ATTACAGGCGTGAGCCACCATGCCCAGCTGAGACTACCTTCTGGATCTGATGAAGTATTAGAAAGGAGC GGGTGGCTTCTCCTTTGTCTCTGGTTTGGCAATCGGAGCTTTCAGGGCACAGTGTTTGTCTCCAGATGT TGATGGAAGTGGGCACTCCTTGGTGGCCTCCAACAGGAAAAGCGTGTTCTTTCATTGTTTCCTATACAC ACAGACAACCGTTTTTCCAGGAAGGCAGCCCCATCTTTAGTCATTGACTGCGGGCCTATCATCAGTCAT GACGAAGACCGAGTTAGGTGTGTGCAGGCCCAGAACTAGCACATCACAGCCCCAGAGTGGGCTCCAAAC CGGTAGACCAGAGAGCCTGCAGGATAATTTCCCCCTTAAGATGGGTAGATTTACTGTTCCACAGCCAAC AGGTGGATACGCGTAACTAGAACAATCTGTCATGGGACTAAGTGGAAGAATCCATCAGCACTACACAG AGCGGACCGACTTACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCC CAACCTGCCATCACGAGATTTCGATTCCACCGCCGC
Restriction Sites	SgfI-RsrII
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006946.4
Synonyms	GTRAP41; SCA5; SCAR14
Summary	Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009]
Locus ID	6712
MW	73.9

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