EFHA1 (MICU2) (NM_152726) Human 3' UTR Clone

Specifications

Product Data
Product Name	EFHA1 (MICU2) (NM_152726) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	1110008L20Rik; EFHA1
ACCN	NM_152726
Insert Size	588 bp
Sequence Data	Insert Sequence (showhide) >SC207641 3’UTR clone of NM_152726 The sequence shown below is from the reference sequence of NM_152726. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TGGAAACAAGCTGGAAAAGGTCTTTTTTAATAAAAGATATAATAGTATGGCAATTATATTGTTCCAAAT GTCAAAATTTGTGATTTTTTAGAAGTACTTGCTATTTATCTTCTTAAGTCTTCATTGATATTCTGTGTG AAATAAGCATGTCTTGTACTTGCTTTCTGATTCATAATTTTATTAAAGAACTTAGTAGAAAGAAAAGTA AGTATAAAAATAGATATTGGATTCTGTCAGAAGGCCTAGATTTGAAATAATGTTTTGTACTTCGGTAAG ATGGAAAACTTAGTGATTCACTGATTTCTTAGACACTCTAATATGATATGCTTTCTGGAAGGATAAAAC AAATACATATGGGAAAAAGTACTTGAGACCAAGGCCAGCATCAATTCCAGACATCTTCATGTTCCTAAT AGGCTAAATGAAGTTAAAAACTTATTTCAGATTTTTCTCATCTGTACCTTATATCTCATAAATTTATTG CATATTTTATGTCAGTAGCTTAGCTGTTTATTGTCTTTAAAATAACATGTAAACTTCAATGTTCTATCT GGAAGCAGAATAAAATATTTACATAGATACAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_152726.3
Synonyms	1110008L20Rik; EFHA1
Summary	Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low (PubMed:24503055, PubMed:24560927, PubMed:26903221). MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium (PubMed:24560927). MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering (PubMed:24560927).[UniProtKB/Swiss-Prot Function]
Locus ID	221154
MW	22.9

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