Silencer of Death Domain (BAG4) (NM_004874) Human 3' UTR Clone

Specifications

Product Data
Product Name	Silencer of Death Domain (BAG4) (NM_004874) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BAG-4; SODD
ACCN	NM_004874
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC207066 3’UTR clone of NM_004874 The sequence shown below is from the reference sequence of NM_004874. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGGAAAAATTAGAAAAAAAAGGATTATGAAAGGATTTAGAACAAAGTGGAAGCCTGTTACTAACTTGA CCAAAGAACACTTGATTTGGTTAATTACCCTCTTTTTGAAATGCCTGTTGATGACAAGAAGCAATACAT TCCAGCTTTCCTTTGATTTTATACTTGAAAAACTGGCAAAGGAATGGAAGAATATTTTAGTCATGAGTT GTTTTCAGTTTTCAGACGAATGAATGTAATAGGAAACTATGGAGTTACCAATATTGCCAAGTAGACTCA CTCCTTAAAAAATTTATGGATATCTACAAGCTGCTTCTTACCAGCAGGAGGGAAACACACTTCACACAA CAGGCTTATCAGAAACCTACCAGATGAAACTGGATATAATCTGAGACAAACAGGATGTGTTTTTTTAAA CATCTGGATATCTTGTCACATTTTTGTACATTGTGACTGCTTTCAACATATACTTCATGTGTAATTATA GCTTAGACTTTAGCCTTCTTGGACTTCTGTTTTGTTTTGTTATTTGCAGTTTACAAATATAGTATTATT CTCTACTTCTTGGTACATTTTGTAGTAATATGTTTAATATAATTATTCAAGAGACTATATTGACAGCCA GATAGTATGGCAGTTCTGAAAAAATTTATATCTTTTCACCACTTGAATATACTGCAATGTGTAGTGAGT AAATTGTCTCCCTTTTTCTATAGATCATTAGGTTAGAGTTTTTTTCTTCTTTTTTTTTTTTTTTTTTTT TTACCACTTCTGCTGTTCATGGTAGTAGTGGAAGGTAAATTTGGAAATGGCATTGACATAAAATGAAAA TGTTTACGGACACTTTTCTTTTTTGCTTTTTTATTGTATTTGGATAAAGATCCACTTAAAAGTTATCTG TTTTTTCCTGTTTTTTTTTTTTTTCCCCAAAGTGTAGTTATGTTTTCACTATTGCTGCTTCTATAGAGG GCATTGTGATAGAGAGTTACAGATGAAACATTAAATGCCACAGTGAGTAGAAATAATTACTACAAAAAG TAATAAATATGATTACTTGGTAATATCATTCTCCATCTAAAATACTAGTTTCACCTGTGAGCAGATTTC AGCTCAGTTTATAGTTAAAAACAATGAGGGTAAAATGGGATTCATGCTCAGGGAATGAATCAGCCATAG TTAGAGTGGGAAATTATTATTTTCTTCATTTAAAGGTAGATTTTATGTTTATTTCCCTAAATTGCATAA GATAAAATTGTCTGTTTAATAAAAAGACATTTATTACCATTATTAACAGTCATTTTAGAGCCAAATTTA AGAAAAGGATATTGAAAGGGTCTTTATTGGCCTTGTTTGGGTAACTCTATGCTGTTAGATAGAAGAGAC TTAGGTAAATAACTTTTTATGTCTGAGGTGAGTACACAATATTGGTTCTTGGAAAAATAGCTGTTTCTT CATAAGATACCCAAGTGATAATTTTTTTTCCCCTAGACTGTCAGGCCTATGAGTAAATACTAAATCTAT TAGCTGTCCCCACTCATAAACCAAACCAAACCAATACAAACAGATGAGGAGAGGAAATGTAGTAAAAAT ACTGGCTGGGTCTTATGATTGGGATGAGTGATTTTATAAGATAATATGGTGATAATTTTATTCTAGGAT TTTATTTTTGGCCTAATATAGGAATGTTTAAAAAAGGCTTTTCTATGAAAATTAGAAATTTATACTTGA AATTAAAAGTCTAGAAGGGGGAGGACCTTAAAGCTAAGCTACCAGTAAGACAATGAATAATTCAGAAGA GAACACTATTCTTTTACTGACTGAGTGCCCAAGATGCCAATTTCCATGAAGTCTTGATTTATATATATG TACACATGTTATGCACATACATGTTTGTTTTCTAACAGTTATTTTTTAAGCTTTTGAGATAATTTTAGA CTTACAGAAGAGTTGTAAAAGTAGTAGAGTTCTTGTATACTCTGCACCCACCTTGCCCTTATGTTAAC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004874.4
Synonyms	BAG-4; SODD
Summary	The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Mar 2011]
Locus ID	9530
MW	78.8

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