C14orf169 (NM_024644) Human 3' UTR Clone

Specifications

Product Data
Product Name	C14orf169 (NM_024644) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C14orf169; hsNO66; JMJD9; MAPJD; NO66; ROX; URLC2
ACCN	NM_024644
Insert Size	481 bp
Sequence Data	Insert Sequence (showhide) >SC206168 3’UTR clone of NM_024644 The sequence shown below is from the reference sequence of NM_024644. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTCACTAAGATGCCTCTAGCCCTAAATTAGTTTCTTGTTGATTGCTGGAAACAAGGCAGTAGTGATTCT CCGCTGCCACTGCTACCTTTTTTTTTTTTTTTTCCTTAAACTCACGTTCTTACCTTGATAAGCATCAGT GTGCTCACATTTACCTTTATCACTGCTTCAGTGTCACAAACCTCGGAAGGTCTTCTAGGAAGAACCATC TCATCTAGGTACAAAAGGAAAAGGAGAAGTTGGAGGTGGAAAAAAAACCCTTGATCCGTGATCATTTCA GAGCACCAACTTCATCACCTTCAGGCTTCAGTGTACTGGGTAACACTGACCATGTCGTTCTGCTTGAGA CAGATATTAGATTTTTTTTGGAATTTGGATCTTTCATCTGAGTTCTTTTTCATGGGCGGGTCGGGGTCA GTATCCTGTTTGTTATTGTTAAATTTGTATGAACCTTAGAAAAGTTATTAAAGTGCCAAAGAATGTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_024644.5
Synonyms	C14orf169; hsNO66; JMJD9; MAPJD; NO66; ROX; URLC2
Summary	Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation.[UniProtKB/Swiss-Prot Function]
Locus ID	79697
MW	18.5

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