Zyxin (ZYX) (NM_003461) Human 3' UTR Clone

Specifications

Product Data
Product Name	Zyxin (ZYX) (NM_003461) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ESP-2; HED-2
ACCN	NM_003461
Insert Size	459 bp
Sequence Data	Insert Sequence (showhide) >SC206061 3’UTR clone of NM_003461 The sequence shown below is from the reference sequence of NM_003461. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGTGCCACACTGCTAGAGCCCAGACCTGAGTGAGGACAGGCCCTCTTCAGACCGCAGTCCATGCCCCA TTGTGGACCACCCACACTGAGACCACCTGCCCCCACCTCAGTTATTGTTTTGATGTCTAGCCCCTCCCA TTTCCAACCCCTCCCTAGCATCCCAGGTGCCCTGACCCAGGACCCAACATGGTCTAGGGATGCAGGATC CCCGCCCTGGGGTCTGGTCCTCGCCCATCCTGCAGGGATTGCCCACCGTCTTCCAGACACCCCACCTGA GGGGGGCACCAGGTTTAGTGCTGCTGCTTTCACTGCTGCACCCGCGCCCTCGGCCGGCCCCCCGAGCAG CCTTTGTACTCTGCTTGCGGAGGGCTGGGAGACCCTCCAGGACATTCCCACCCTCCCCCATGCTGCCAA GTTGTAGCTATAGCTACAAATAAAAAAAAACCTTGTTTTCCAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003461.5
Synonyms	ESP-2; HED-2
Summary	Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008]
Locus ID	7791
MW	16.4

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