Protor 1 (PRR5) (NM_015366) Human 3' UTR Clone

Specifications

Product Data
Product Name	Protor 1 (PRR5) (NM_015366) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FLJ20185k; PP610; PROTOR-1; PROTOR1
ACCN	NM_015366
Insert Size	464 bp
Sequence Data	Insert Sequence (showhide) >SC205855 3’UTR clone of NM_015366 The sequence shown below is from the reference sequence of NM_015366. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGCTCTGGGGGCCGGCAGAGTGTCGTGTGAGGCCTCACAGCTGGCCTTGAGTTTTTACTGACACGTCCC TGTGTGCGGGGGTGTCCATGTGGCGTGTGTGTGAGTGAGACTTTTTTACTGCGTCCCGTCCCGCCAGCC CTATCGGCCTCGTCACTGGCCTTGGTCACTTTGTATTTCTGTCTTGGTTGGAAATACCATCAGCCTTCC TTGCTCGGCCCAGGTCTGTTTCAGGCATCTGAGTCGGCGTTTACCCAGGGGCCGGGCCAGAGACGGGGG TCGGCCGCTCGCTCCCACGCTCCTCCTGCCCCAGCCCTCTGGTGTCCACACCTGCCCACAGAGAATGTA AACCCAGTGGGCTCTGCCCACGCCGGGCCCCAAAGTGACCAGACTCCAGCACACCTGTCTCCTCCTGCC TGGGGTGGCCATGGGGATGGAAGGGGGTGGAATAAAACCTGTCAACCTGG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015366.4
Synonyms	FLJ20185k; PP610; PROTOR-1; PROTOR1
Summary	This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq, Nov 2010]
Locus ID	55615
MW	16

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