MyoGEF (PLEKHG6) (NM_001144857) Human 3' UTR Clone

Specifications

Product Data
Product Name	MyoGEF (PLEKHG6) (NM_001144857) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MyoGEF
ACCN	NM_001144857
Insert Size	391 bp
Sequence Data	Insert Sequence (showhide) >SC205076 3’UTR clone of NM_001144857 The sequence shown below is from the reference sequence of NM_001144857. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACACCCCTCTGTCCGCATCAGAGGTATGAGGAATGCAGAGGACCTTTGGCATGCATCTCTCCCAGAGG AGATCTCTCCCCAGTAGTGCTGGTCACCCTCCGGCATCTGTGACTCTACCTCAAGGACCACATTTCCCA AAGGAAGCCTGGCCCAGGCACCCTGCCTCCTGCTCTGTTTGGGGATCAAGAACTGTAAATTTATGTATC ATAGGTGCACCTGAGCCCCACAGAAAGTTGTGCATAAAAATGACTGCCCTGGCTGGGCATGGCTGCCTG TAATCCCAGCACTTTGGGAGGCTGAGGTGGGAGGATCCCTTGAGCCCAGGAGTTCCAGACCAGCCTGGG CAATATAGGGAAACCCTGTCTTTACAAAAAAAAATTTTAAAAATTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001144857.2
Synonyms	MyoGEF
Summary	Guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. Also activates RHOG. Does not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving PLEKHG6, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.[UniProtKB/Swiss-Prot Function]
Locus ID	55200
MW	14.3

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