SELK (SELENOK) (NM_021237) Human 3' UTR Clone

Specifications

Product Data
Product Name	SELK (SELENOK) (NM_021237) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HSPC030; HSPC297; SELK
ACCN	NM_021237
Insert Size	1171 bp
Sequence Data	Insert Sequence (showhide) >SC205030 3’UTR clone of NM_021237 The sequence shown below is from the reference sequence of NM_021237. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTCCAATGGCTGGTGGATGAGGAAGGTAAATGTCTGCTCTAAGAAGCAGACAACCGGACATGCGCATT CATAGCAGAAGGAAACCATCAAGAAGTGGAAGGCTGACCATGATGAGCAGTAGATGAATGTGTATGTCT AAACAAGGACTGCTCTGTGTCCTCACAGATGAATGAGGTCATGCTGGGAATTCCCTCTGCAGGGAACTG GCCTGACTGACATGCAGTTCCATAAATGCAGATGTTTGTCTCATTACCTTTTTGTATAGTTTATTAAAG TATTAATATAGTTTTAATAAGTAAATATTTTTAGGTTGCAGAATGGACTCCTCATCTTTATATTCACGA AAAAGCAATCTGAAGAAAACAAATAAAAGCCTGTGTATTTAGCACTGTTAGTGTCACCTTTTCAACTTC TGAAACACTGTTCATTGTTAACTTTTTCTCATTTATAAATCACTGTATTTATTTTAGTAGTATGCATAG CATATCTGTGCTCTTGAATTAATTTTTATCTTTAACATATTTGTCTCATCAATCTTTAATACACTGTGT CTAATTTGCTACCAAATGTAATTATCAGGGTATTTATAAAACCATAGCTAACAAAACTGAGCTACAAAA TGAAAATTTACTAAATAGTTTTTAAAATCATGGACTTCAGCCTGGCGCGGTGGCTCATGCCTGTAATCC CAGCACTGTGGGAGGCTGAGGCGGGCAGATCGCCTAAGTTCACGAGTTTGAGACCAGCCTGCAGCATGA CGAAACCTAAAATAACAAAAATTAGCCAGGCGTGGTAGAGTGCACCTGTAATCCCTGCTACTCAGGAGG CGGAGGCAGGAGAATCGCTTCAACCCGGGAGGCGGAGGTTGCTGTGAGCATGCCACTGCACTCCTGCCT AGGCAACAGAGTGAGACCCTGTCTCAAAAAAATAAATAAAACCATGGGCTTCCATGCTATCTTGACAAA TTTGCACTCTATAGCATCACTCAAAATACTGCCTATTGGCTTTAAACTCCATCTGAATACTGATAACTT TCACATTCTTTCACTAGAGTGGAAGCTCTGAGACTAGGAATTTTGTTGTCTTTACCCCAGTCCTTTGAA TAGTGACTACATGTAAGATAGTCATGTAGTATTTATTGGAAATAAATATTTATTGGAAAAACGAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_021237.5
Synonyms	HSPC030; HSPC297; SELK
Summary	The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER stress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Pseudogenes of this locus have been identified on chromosomes 6 and 19.[provided by RefSeq, Aug 2017]
Locus ID	58515
MW	44.8

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.