EVA1 (MPZL2) (NM_144765) Human 3' UTR Clone

Specifications

Product Data
Product Name	EVA1 (MPZL2) (NM_144765) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DFNB111; EVA; EVA1
ACCN	NM_144765
Insert Size	369 bp
Sequence Data	Insert Sequence (showhide) >SC204917 3’UTR clone of NM_144765 The sequence shown below is from the reference sequence of NM_144765. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTCTCTGTTTATTTAGAAGACACAGACTAACAATTTTAGATGGTAAGGTTCACAAATAGGTTGATTTCT TTCTTCAGCTTTCTGACATGTCCAGCCCATCTCTAATGAGGACTCCCAGATCATCACTTTATGGCTGTT AGGTGTTTCCCATATGAAATTAGAGGAGCTGGGTCAGGGAGACAAAAGTCTTCTATTAGTCTTATGGAT AGCTCCTCCTTGAGTGTATTTTGTGCAAAAGATTAAGAAGCTGGACTCTACTGCCATTAAAGCTGAGAG AATCCTAAGGTTATTTGTGGCTTCGGGGTTATATTTATTACTACTACTACTAATAAATATTCAACAAGT AAATAAATCTTTTTTAAATCAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_144765.3
Synonyms	DFNB111; EVA; EVA1
Summary	Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. Epithelial V-like antigen (EVA) is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. It is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The protein bears a characteristic V-type domain and two potential N-glycosylation sites in the extracellular domain; a putative serine phosphorylation site for casein kinase 2 is also present in the cytoplasmic tail. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Locus ID	10205
MW	13.9

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