AGR2 (NM_006408) Human 3' UTR Clone

Specifications

Product Data
Product Name	AGR2 (NM_006408) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AG-2; AG2; GOB-4; HAG-2; HEL-S-116; HPC8; PDIA17; XAG-2
ACCN	NM_006408
Insert Size	1127 bp
Sequence Data	Insert Sequence (showhide) >SC203613 3’UTR clone of NM_006408 The sequence shown below is from the reference sequence of NM_006408. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCTCTCAAGTTGCTGAAGACTGAATTGTAAAGAAAAAAAATCTCCAAGCCCTTCTGTCTGTCAGGCCTT GAGACTTGAAACCAGAAGAAGTGTGAGAAGACTGGCTAGTGTGGAAGCATAGTGAACACACTGATTAGG TTATGGTTTAATGTTACAACAACTATTTTTTAAGAAAAACAAGTTTTAGAAATTTGGTTTCAAGTGTAC ATGTGTGAAAACAATATTGTATACTACCATAGTGAGCCATGATTTTCTAAAAAAAAAAATAAATGTTTT GGGGGTGTTCTGTTTTCTCCAACTTGGTCTTTCACAGTGGTTCGTTTACCAAATAGGATTAAACACACA CAAAATGCTCAAGGAAGGGACAAGACAAAACCAAAACTAGTTCAAATGATGAAGACCAAAGACCAAGTT ATCATCTCACCACACCACAGGTTCTCACTAGATGACTGTAAGTAGACACGAGCTTAATCAACAGAAGTA TCAAGCCATGTGCTTTAGCATAAAAGAATATTTAGAAAAACATCCCAAGAAAATCACATCACTACCTAG AGTCAACTCTGGCCAGGAACTCTAAGGTACACACTTTCATTTAGTAATTAAATTTTAGTCAGATTTTGC CCAACCTAATGCTCTCAGGGAAAGCCTCTGGCAAGTAGCTTTCTCCTTCAGAGGTCTAATTTAGTAGAA AGGTCATCCAAAGAACATCTGCACTCCTGAACACACCCTGAAGAAATCCTGGGAATTGACCTTGTAATC GATTTGTCTGTCAAGGTCCTAAAGTACTGGAGTGAAATAAATTCAGCCAACATGTGACTAATTGGAAGA AGAGCAAAGGGTGGTGACGTGTTGATGAGGCAGATGGAGATCAGAGGTTACTAGGGTTTAGGAAACGTG AAAGGCTGTGGCATCAGGGTAGGGGAGCATTCTGCCTAACAGAAATTAGAATTGTGTGTTAATGTCTTC ACTCTATACTTAATCTCACATTCATTAATATATGGAATTCCTCTACTGCCCAGCCCCTCCTGATTTCTT TGGCCCCTGGACTATGGTGCTGTATATAATGCTTTGCAGTATCTGTTGCTTGTCTTGATTAACTTTTTT GGATAAAACCTTTTTTGAACAGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006408.4
Synonyms	AG-2; AG2; GOB-4; HAG-2; HEL-S-116; HPC8; PDIA17; XAG-2
Summary	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]
Locus ID	10551
MW	43

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