BLNK (NM_001114094) Human 3' UTR Clone

Specifications

Product Data
Product Name	BLNK (NM_001114094) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AGM4; BASH; bca; BLNK-S; LY57; SLP-65; SLP65
ACCN	NM_001114094
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC203590 3’UTR clone of NM_001114094 The sequence shown below is from the reference sequence of NM_001114094. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGACTGAAGTATGCAGTTAAAGTTTCATAAAGGGGGAAAAAAAAGATCAATACCATTGCTTCAGACACT TTCCCAAAGTTTCTCCTTTTGAGAAAAAGTCCCAAAACTTCATATTTTGGATTATGAATCATCCAGTAA TAAAATGGAAGATGGAGTCAGCTATTGAAGTGGTCATCCATTTCTTTTTAAGAAGCTCATGTGGACTTG TTCTATTGCCTGACCTGATGAACTGTTAATATCTGGTGAGGTTGAGTTATCATGCTACTAATATTTTCC AAATAAATATTTTTATTTTTAAAAATAAGTGTAAAGTATATTATCAAAATAAGAAAATAATGCTCTTGC ATAAAACAAAGTGGCTGGAAATTTAAACCTCCACAATGATCATTGGTACACTAATGTAGCTGGGCTCTC CACTGCCAATGCTTGACAATTAAGTCTTGGTTAAAATTTTAATTTGTAGAAAATAAGGTATTAAAGGTA ATGTATGATATCTGTAAGTATAGGCAAGAAGGATGTAATGGTTCCTTTTTGTGAGCACTCTCAACCATG GGATATATATATATATGGATATGAACTTTCTATAAGTTCTTGTCTAGGATTATGCTGTTAGTTTTGCTT ACTAAAGATAATTATACCCTCTTTGATCTACATGTCTATCAAATAGAACCTAAACTTGATATGAGGTTT GTATTAGTCCATTATCACGCTGCTAATAAAGACATACTCAAGACTGGGTGATTTACATAAAAAAAAAAA AAAAAAAAGAGGTTTAATGGACTCACAGTTCCACATGGTTGGGGAGGCCTCACAATCATGGCAGAAGGC AAAGAAGAAGCAAAGGCATGTTTTACATGGTGGCAGGCAAGAGAGCATGTGCAGGGGAACTGCCCTTTA TAAAACCATCAGATCTCATGAGACTTACTCACTATCACAACAACATGGGAAAACCTGCCCGCGTGATTC AGTTACCTCCCACCAGGTCCCTCCCATGGCACGTGGGGATTATGGGAGCTACAATTCAAGATGAGATTT GGGTGAGGACACAGCCAAACCATATCAAGTTTCAAAGTGGAATGACAGCAAAGCTAGACTAAAAGCCAG TTCCTAGAGAAATATCCCACAAAACAAGAGCAGAAAAGCAGACATTGGTGAACACCAAGGAATAAAAGA GATACCATCGTGGAGAATCAGGTCCAAGGTCTTAGATCATCCCAGAAATGTATCATACTTTGTCATATA TTTCTACTGTGTACTTCAGACAGCAGTGAAGTGATAAAGCAGCTAATTAAGTCTAATAATTAAATGGGG AACACACTTGGCCACTGCATAAGATAGCAATCTATGAAAGTATGTTGAAAGGCCAGAAGGTAATAATTT CAGGGTAACTCATGACTCACTTCTAAAGATAATTGTATATTTAAATGTCATAAACTTTCATAATTGCCA CCTATGTTACAGATTGAACTGTGGTCCCCTCAAAAAGATATGTTGAAGTCCTAATCCATAAGGCCACAT ATCTCAGAATGTGACCTTATTTGGGAATGAGGTCTTTACAGATATAGTCAAGGTAAGATGAGGTCAGTA GGGTGGGCCTTAATACAATGGCTGGTGTCCTTATAAAATTAGGAAATTTGGATGCAGGCACAGAGAGAA GACTATATGAAGAGACACACAGGAACAATACTACTGGCGTGATTCCATCCTGTATGGCTGTTCTCTTGA GCAGTGGTCGTTTATCTCCGTCTGCTTTCTCTCCCACCTAAGTGTGTGCCGCCACCTGATGGAAGATTC GATGGACATGGACGTGAGCCCCCTGAGGCCCAGAACTATCTTTTCAGTTGTGAACTAAAGGCCGACAAA GATGATCACTTTAAGGTGGATAATGATGAAAATGAGCACCAGTTATCCTTAAGAACGGTCAGTTTAGGG GCTGGTGCAAAGGATGAACTGCACATTGTTGAAGCAGAGGCAATGAATTATGAAGGCAGTCCAATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001114094.2
Synonyms	AGM4; BASH; bca; BLNK-S; LY57; SLP-65; SLP65
Summary	This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Locus ID	29760
MW	77.4

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