Neuroserpin (SERPINI1) (NM_005025) Human 3' UTR Clone

Specifications

Product Data
Product Name	Neuroserpin (SERPINI1) (NM_005025) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HNS-S1; HNS-S2; neuroserpin; PI12
ACCN	NM_005025
Insert Size	276 bp
Sequence Data	Insert Sequence (showhide) >SC203340 3’UTR clone of NM_005025 The sequence shown below is from the reference sequence of NM_005025. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACAAGTGGACATGATTTCGAAGAACTTTAAGTTACTTTATTTGAATAACAAGGAAAACAGTAACTAAGC ACATTATGTTTGCAACTGGTATATATTTAGGATTTGTGTTTTACAGTATATCTTAAGATAATATTTAAA ATAGTTCCAGATAAAAACAATATATGTAAATTATAAGTAACTTGTCAAGGAATGTTATCAGTATTAAGC TAATGGTCCTGTTATGTCATTGTGTTTGTGTGCTGTTGTTTAAAATAAAAGTACCTATTGAACATGTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005025.5
Synonyms	HNS-S1; HNS-S2; neuroserpin; PI12
Summary	This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Locus ID	5274
MW	10.5

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