Geminin (GMNN) (NM_015895) Human 3' UTR Clone

Specifications

Product Data
Product Name	Geminin (GMNN) (NM_015895) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Gem; MGORS6
ACCN	NM_015895
Insert Size	330 bp
Sequence Data	Insert Sequence (showhide) >SC203092 3’UTR clone of NM_015895 The sequence shown below is from the reference sequence of NM_015895. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCTCTACGGATGCAAAGCCATGTATATGAAATGCATTAATATTTGACTGTTGAGAATTTTACTGCCGA AGTTTACCTCCACTAGTTCTTTGTAGCAGAGTACATAACTACATAATGCCAACTCTGGAATCAAATTTC CTTGTTTGAATCCTGGGACCCTATTGCATTAAAGTACAAATACTATGTATTTTTAATCTATGATGGTTT ATGTGAATAGGATTTTCTCAGTTGTCAGCCATGACTTATGTTTATTACTAAATAAACTTCAAACTCCTG TTGAACATTGTGTATAACTTAGAATAATGAAATATAAGGAGTATGTGTAGAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_015895.5
Synonyms	Gem; MGORS6
Summary	This gene encodes a protein that plays a critical role in cell cycle regulation. The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1, preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex. The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition. Increased expression of this gene may play a role in several malignancies including colon, rectal and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and two pseudogenes of this gene are located on the short arm of chromosome 16. [provided by RefSeq, Oct 2011]
Locus ID	51053
MW	12.9

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