Selenoprotein M (SELENOM) (NM_080430) Human 3' UTR Clone

Specifications

Product Data
Product Name	Selenoprotein M (SELENOM) (NM_080430) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SELM; SEPM
ACCN	NM_080430
Insert Size	223 bp
Sequence Data	Insert Sequence (showhide) >SC202923 3’UTR clone of NM_080430 The sequence shown below is from the reference sequence of NM_080430. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGGAAACTTCGGACCACGCTGACCTGTAGGTCCGGGGGCGCGGCGGAGCTGGGACCTACCTGCCTGAG TCCTGGAGACAGAATGAAGCGCTCAGCATCCCGGGAATACTTCTCTTGCTGAGAGCCGATGCCCGTCCC CGGGCCAGCAGGGATGGGGTTGGGGAGGTTCTCCCAACCCCACTTTCTTCCTTCCCCAGCTCCACTAAA TTCCCTCCTGCCTTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_080430.4
Synonyms	SELM; SEPM
Summary	The protein encoded by this gene belongs to the selenoprotein M/SEP15 family. The exact function of this protein is not known. It is localized in the perinuclear region, is highly expressed in the brain, and may be involved in neurodegenerative disorders. Transgenic mice with targeted deletion of this gene exhibit increased weight gain, suggesting a role for this gene in the regulation of body weight and energy metabolism. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. [provided by RefSeq, Dec 2016]
Locus ID	140606
MW	7.9

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