S4 (PSMC1) (NM_002802) Human 3' UTR Clone

Specifications

Product Data
Product Name	S4 (PSMC1) (NM_002802) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	P26S4; p56; RPT2; S4
ACCN	NM_002802
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC202480 3’UTR clone of NM_002802 The sequence shown below is from the reference sequence of NM_002802. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGGCACCCCTGAGGGGCTGTATCTCTAATGAACCATGGCTGTCATCAGGAAAATGGTTGGGAGATTT CTCAATCCCTGAAAGGGATGAGGTTGGGGGAGTTGCCCAGAGGAATCCCTGTTCCCACTGATTTTTATT AGCAAAACATCCTGTGTCTTTTGGAGTACGATGTGTAAGTGCCCATTGGGTGGCCTGTTGGTCACTGTG CAGCAGTCTGCTTCCCAATAAAGCGTGCTCTTTCACAAACACTTCCTGTTTCTGCAGTCTCCACACACA CCTACCGCTCAACAGCAGCCTGTGGGTGGACCCAGCTACAGGGAAGCCTTTGGACAGGAACTCAGGCTG CGGTCCCAAGGAGTGTGGACCTCACTATGCGTTCGCCACATCACACCCCCAGAGCTGGCGTTCAACGGT AATTACAGTGGGAAATGGTCACTACCACAGAGCCAGGGATATTCGTTGTTTAAATAATAAAGGCTGCGT TAATGTGGCTATTGCTTCCAAAGGAAGTACAGCTTTCCTTTTTGGAAGTTTTGTGGACCATGCATGTTC TTAGCACTCTGAGGGCAGAAAATAACTACTGGTGTTCCCAAGAGACTGAGGATTCCTAGAGATATCTTG AAAGCCCTTCTGAGCCCTTGGGCTCAGAAATCTCATCCCTTTCAAGGTGTTCAGAAACATGTCAGAACT TCCCCTTCCCTTTCTCCGTCTATTTCCGTCATTTCTCTTTCTGAACAAATCAGGCCTAAAGCTATTAAG TGGGACAGATCAAGGTAAGCGTTCCCTTGACAGGTGGCCTGGTGTGGGTTGTAGGGCCCACACTGAATG AGGAGTGTGTATTAGTTTTCTGTTAATACTATAACAAGTTACCACAGGCTTTGTTTAAAAACAGCACAA TTTGGCCAGGCACGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGCTGAGGCAGGCGGATCACAA GGTCAGAAGTTTGAGGCCAGCCTGGCCAACATGGTGAAACCCCATCTTTACTAAAAATACAAAAATTAG CTGTGCGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGACAATCGCTTGAACC CAGGAGGCGGAGGTTGCAGTGAGCCAAGATCCCGTCACTGCACTCCAGCCTGGGCGACAGAGCAAGACT CCGTCTCAAAAATAAATAAATAAATAAATAAAAACCACAATTTTATCTCAGTTCTGTAGGTCAGAAGTC CAACACGAGTGTCTCCAGGCTAAAGTCTTGCTGTTGGCAGGACCGTTCCCTCTGGCGTCTCTAAGGGAG AATCCGTTTCCTTGCTGAGGATTATTGTTGGCAGAATTTAATTTCTTGGAGTTGTGGGCCAGCTGAGGT CAGCATTTCCTTGCTGGCTGCCAGCTGAGGCCTTTGCCAGTCTGTGAAGGCCACCCTCCCTCCTGACTC GTGGCACTTCATTTTCCACCAGCAGCAGCAGGCCCAGTCCCTCTCTCCCACCGACCCTTCTTTCTGCCT GCCTTTTCTATTCTTATGGATCCTTGTGATTGCATTGGACCCATGCAGATGATCCAGGATAATTTCCCT GTTTTAAAGTTTACAATCTTCTTAATTTTTATCTGCAAAGTTCCTTTTGCCATGTAACATTCACACGTT CCAGGGCTTAGGGTGTGGCCATCTTTAGGGGCGCCACTCTGCCTACCACAGAGGACATCCACACGTGGG GGTGGCCCAGTGCAGGGTAAGGACGGGGTGCTTGTGGGGAGGGCGGGTGTCAGCCCAAGTAGGGTGTGG AGCTGTCCATGTGGAGGAACACCACAGCACGGGGACTCAGCATGGGCAGGGTGAGGCTGGCATCCGTGT GGGGTGTATGTGCAGGGCTGGGGTGGTCCGATAGGGGGAGTCAGTGTGGGCAGCCTGATGTGCAGTATG AGAGCCCAAGTGGGTGAGGAAGGCATCTGCAGGGACGGGGTGGTGGCAGGGGAGGGAGGCTGCTTATG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002802.3
Synonyms	P26S4; p56; RPT2; S4
Summary	The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. This subunit and a 20S core alpha subunit interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. This subunit also interacts with the adenovirus E1A protein and this interaction alters the activity of the proteasome. Finally, this subunit interacts with ataxin-7, suggesting a role for the proteasome in the development of spinocerebellar ataxia type 7, a progressive neurodegenerative disorder. [provided by RefSeq, Jul 2008]
Locus ID	5700
MW	72.9

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