FBXL15 (NM_024326) Human 3' UTR Clone

Specifications

Product Data
Product Name	FBXL15 (NM_024326) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Fbl15; FBXO37; JET; PSD
ACCN	NM_024326
Insert Size	173 bp
Sequence Data	Insert Sequence (showhide) >SC201634 3’UTR clone of NM_024326 The sequence shown below is from the reference sequence of NM_024326. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTCGCACCTTTTGTCAACCTGCAGGTCTGACCCGCCTGCCAATCGGAGCACAGCTGGACTGTGTGGCTG GGGCCTGACACTGAGCTGTAGGGAAACTGAACTGTGAGGACCTCTGGTGAGAGGCCAGTGCCCTGCCCC ACCCTGGAGCTTCAAATAAAGAGCTTTTTACCCCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_024326.4
Synonyms	Fbl15; FBXO37; JET; PSD
Summary	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.[UniProtKB/Swiss-Prot Function]
Locus ID	79176
MW	6.4

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