TBC1D17 (NM_024682) Human 3' UTR Clone

Specifications

Product Data
Product Name	TBC1D17 (NM_024682) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_024682
Insert Size	156 bp
Sequence Data	Insert Sequence (showhide) >SC201320 3’UTR clone of NM_024682 The sequence shown below is from the reference sequence of NM_024682. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGGAGGAGGACGAGGGCGCCGACTCCTAACCCCGCCAGGCAGCCTCGTTCTGCACAGGCACTTTAGCC CGAGCCAGGCACACCTGCGAGGGGGCAGGTGTGCTCCGCCGCCCTGCTGATAAGCTGGCTTCATTAAAC TGACACTTCTCATGTGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_024682.3
Summary	Probable GTPase-activating protein for Rab8; its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor (TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment (ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50; the function requires its catalytic activity, however, the involved Rab is not known.[UniProtKB/Swiss-Prot Function]
Locus ID	79735
MW	5.5

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