GPS2 (NM_004489) Human 3' UTR Clone

Specifications

Product Data
Product Name	GPS2 (NM_004489) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AMF-1
ACCN	NM_004489
Insert Size	125 bp
Sequence Data	Insert Sequence (showhide) >SC200934 3’UTR clone of NM_004489 The sequence shown below is from the reference sequence of NM_004489. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGCCAGAACCCGCGATTCTACCACAAGTGACCATCAGATTATATCTTCAACACCACACCCCCCACCCCA TCGTGGGTGAGGGTATCCCCTGTGTGTCCCAGGCCAATAAAATCTACCTGCCACTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004489.5
Synonyms	AMF-1
Summary	This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]
Locus ID	2874
MW	4.8

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