SETD4 (NM_001007259) Human 3' UTR Clone

Specifications

Product Data
Product Name	SETD4 (NM_001007259) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	C21orf18; C21orf27
ACCN	NM_001007259
Insert Size	105 bp
Sequence Data	Insert Sequence (showhide) >SC200491 3’UTR clone of NM_001007259 The sequence shown below is from the reference sequence of NM_001007259. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCAAGAGGTTGGAATCAACTTTGTTCTTAACATTAACACTATATAATTTTTTTCCCCATTTGGAGATGT GTATTTTCAGTTTTAATAAAAATATCAAAACCTTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001007259.3
Synonyms	C21orf18; C21orf27
Summary	Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response (PubMed:31308046). Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively), leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity). Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3), thereby promoting heterochromatin formation (PubMed:31308046). Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	54093
MW	4.1

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