SPINK5 (NM_001127699) Human 3' UTR Clone

Specifications

Product Data
Product Name	SPINK5 (NM_001127699) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	LEKTI; LETKI; NETS; NS; VAKTI
ACCN	NM_001127699
Insert Size	131 bp
Sequence Data	Insert Sequence (showhide) >SC200489 3’UTR clone of NM_001127699 The sequence shown below is from the reference sequence of NM_001127699. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCTCAAATAATGCAAAGGTTATTTATTAAAGGATACCAAAATAACCATTTTACTTTTCACCTTCAGAA TTTTGCATTCTTCTCCAGCTTTGGGAATAATAAATATATTAATATCTTAACTTCAAAGAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001127699.2
Synonyms	LEKTI; LETKI; NETS; NS; VAKTI
Summary	This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Locus ID	11005
MW	5.3

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