Mouse Gdf2 ELISA KIT (96 T)

Specifications

Product Data
Description	Mouse BMP-9 Immunoassay
Size	96 T
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	7.8-500 pg/ml
Sample Type	Serum, plasma, Cell culture supernatant
Sample Volume	100 uL
Specificity	This assay recognizes both natural and recombinant Mouse BMP-9
Sensitivity	4 pg/mL
Reactivity	Mouse
Interference	No significant interference observed with available related molecules.
Components	Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate Standard - lyophilized,2000 pg/ml upon reconstitution,2 vials Concentrated Biotin-Conjugated antibody(100X) - 120 ul/vial,1 vials Concentrated Streptavidin-HRP solution(100X) - 120 ul/vial,1 vial Standard /Sample Diluent - 16 ml/vial,1 bottle Biotin-Conjugate antibody Diluent - 16 ml/vial,1 bottle Streptavidin-HRP Diluent - 16 ml/vial,1 bottle Wash Buffer Concentrate (20x) - 30 ml/vial,1 bottle Substrate Solution - 12 ml/vial,1 bottle Stop Solution - 12 ml/vial,1 bottle Plate Cover Seals,4 pieces
Background	Bone morphogenetic protein 9 (BMP-9), also known as growth and differentiation factor 2 (GDF-2), is a member of the BMP family of TGF-β superfamily proteins that signal through heterodimeric complexes composed of type I and type II BMP receptors. BMP-9 regulates the development and function of a variety of embryonal and adult tissues. Mouse BMP-9 consists of a 22 amino acid (aa) signal sequence, a 296 aa propeptide, and a 110 aa mature protein. Unlike other BMP family propeptidesthe BMP-9 propeptide does not interfere with the biological activity of BMP9, and remains associated with the mature peptide after proteolytic cleavage. BMP-9 is expressed by non-parenchymal cells in the liver where it promotes lipid metabolism and inhibits glucose production. It exerts a prolonged hypoglycemic effect which may be due to an enhancement of insulin release.
Gene Symbol	Gdf2
Locus ID	12165

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