Mouse Il15ra ELISA KIT (96 T)
CNY 3200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Mouse IL-15 Ra Immunoassay |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 125-8000 pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Specificity | This assay recognizes both natural and recombinant mouse IL-15Ra. |
Sensitivity | 60pg/mL |
Reactivity | Mouse |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | IL-15 Ra (Interleukin 15 Receptor alpha), also known as CD215, is a transmembrane glycoprotein that plays an important role in NK and CD8+ memory T cell homeostasis and activation. It transmits IL-15 induced signals and additionally interacts with a complex of IL-2 R beta and the common gamma chain (gammaC) which are also subunits of the IL-2 receptor complex. In transpresentation, IL-15/IL-15 Ra complexes are expressed on the surface of one cell and interact with complexes of IL-2 R beta/gammaC on adjacent cells. IL-15/IL-15 Ra complexes can transmit reverse signaling that promotes adhesion and activation of the IL-15/IL-15 Ra expressing cells. Shed soluble forms of IL-15 Ra retain the ability to bind tightly to IL-15 and can inhibit IL-15 bioactivity. |
Gene Symbol | Il15ra |
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