Human Fetuin B (FETUB) ELISA KIT (96 T)
CNY 3200.00
货期*
3周
规格
Specifications
Product Data | |
Description | Human Fetuin B Immunoassay |
Size | 96 T |
Format | 96-well strip plate |
Assay Type | Solid Phase Sandwich ELISA |
Assay Length | 4 hours |
Signal | Colorimetric |
Curve Range | 93.75-6000pg/ml |
Sample Type | Serum, plasma, Cell culture supernatant |
Sample Volume | 100 uL |
Specificity | This assay recognizes both natural and recombinant human Fetuin B |
Sensitivity | 15pg/mL. |
Reactivity | Human |
Interference | No significant interference observed with available related molecules. |
Components |
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Background | Fetuins are members of the cystatin superfamily of cysteine protease inhibitors. Additional members of this superfamily are kininogen and histidine-rich glycoprotein. Fetuin A and B are two known members of the fetuin family. Hepatocytes are believed to be the principal cellular source, but other cell types also express it. Fetuin A, also known as α2-Heremans-Schmid glycoprotein, is an inhibitor of basic calcium phosphate precipitation and a negative acute-phase protein. Fetuin B is a newer member whose function is not fully characterized. Fetuin A and B display similarities and differencesin their characteristics. Fetuin B exhibits reduction of calcification, while both mRNA levels were down-regulated during the acute phase in inflammation-induced rats. However, they share only 20% amino acid sequence identity. The amounts of Fetuin B in human serum, unlike Fetuin A, vary with gender and are higher in females than in males. |
Gene Symbol | FETUB |
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