Human IL19 ELISA KIT (96 T)

Specifications

Product Data
Description	Human IL-19 Immunoassay
Size	96 T
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	4 hours
Signal	Colorimetric
Curve Range	31.25-2000pg/ml
Sample Type	Serum, plasma, Cell culture supernatant
Sample Volume	100 uL
Specificity	This assay recognizes both natural and recombinant human IL-19
Sensitivity	15 pg/mL
Reactivity	Human
Interference	No significant interference observed with available related molecules.
Components	Microwell Plate - antibody coated 96-well Microplate (8 wells ×12 strips),1 plate Standard - lyophilized,2000 pg/ml upon reconstitution,2 vials Concentrated Biotin-Conjugated antibody(100X) - 120 ul/vial,1 vials Concentrated Streptavidin-HRP solution(100X) - 120 ul/vial,1 vial Standard /Sample Diluent - 16 ml/vial,1 bottle Biotin-Conjugate antibody Diluent - 16 ml/vial,1 bottle Streptavidin-HRP Diluent - 16 ml/vial,1 bottle Wash Buffer Concentrate (20x) - 30 ml/vial,1 bottle Substrate Solution - 12 ml/vial,1 bottle Stop Solution - 12 ml/vial,1 bottle Plate Cover Seals,4 pieces
Background	Interleukin 19 (IL-19) is a member of the IL-10 family of class II α-helical cytokines that contains viral and cellular homolog proteins. Mature human IL-19 is secreted as a 35-40 kDa N-glycosylated monomer. It shares 69% amino acid (aa) sequence identity with mouse and rat IL-19. Under normal conditions, IL-19 expression is primarily restricted to monocytes. Upon inflammatory stimulation, it is upregulated in monocytes as well as in keratinocytes, smooth muscle cells, and airway epithelial cells. IL-19 induces the release of inflammatory mediators and KGF from monocytes, dendritic cells, lung epithelial cells, hepatocytes, or CD8+ T cells. It drives T-helper cell differentiation towards a Th2 response, inducing both IL-10 and additional production of itself.
Gene Symbol	IL19
Locus ID	29949

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