Human IL17F ELISA KIT (96 T)
CNY 3200.00
货期*
3周
规格
Specifications
| Product Data | |
| Description | Human IL-17F Immunoassay |
| Size | 96 T |
| Format | 96-well strip plate |
| Assay Type | Solid Phase Sandwich ELISA |
| Assay Length | 4 hours |
| Signal | Colorimetric |
| Curve Range | 25-1600pg/ml |
| Sample Type | Serum, plasma, Cell culture supernatant |
| Sample Volume | 100 uL |
| Specificity | This assay recognizes both natural and recombinant human IL-17F. |
| Sensitivity | 12 pg/mL |
| Reactivity | Human |
| Interference | No significant interference observed with available related molecules. |
| Components |
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| Background | The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries. |
| Gene Symbol | IL17F |
| Locus ID | 112744 |
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