Human IL-1 beta ELISpot Kit, 5 x 96-well (pre-coated plates)

Specifications

Product Data
Description	Human IL-1 beta ELISpot Kit, 5 x 96-well (pre-coated plates)
Size	5 x 96 wells (pre-coated plates)
Format	5 x 96-well (pre-coated plates)
Assay Type	Enzyme-Linked ImmunoSpot (ELISpot)
Assay Length	3h after cell stimulation
Signal	Colorimetric
Specificity	Recognizes natural (pro and mature) human IL-1b
Cross Reactivity	No cross reactivity with other human cytokines
Components	Pre-coated ELISpot kits include precoated PVDF plates, Detection antibody, Alkaline phosphatase conjugate, BSA, BCIP/NBT ready-to-use substrate buffer.
Background	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008]
Gene Symbol	IL1B
Locus ID	3553

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