Human TNF alpha ELISpot Kit, 5 x 96-well (pre-coated plates)

Specifications

Product Data
Description	Human TNF alpha ELISpot Kit, 5 x 96-well (pre-coated plates)
Size	5 x 96 wells (pre-coated plates)
Format	5 x 96-well (pre-coated plates)
Assay Type	Enzyme-Linked ImmunoSpot (ELISpot)
Assay Length	3h after cell stimulation
Signal	Colorimetric
Specificity	Recognizes natural human TNF-a
Cross Reactivity	No cross reactivity with other human cytokines. Cross reacivity with macac TNF-a. No interference with TNFR I and TNFR II
Components	Pre-coated ELISpot kits include precoated PVDF plates, Detection antibody, Alkaline phosphatase conjugate, BSA, BCIP/NBT ready-to-use substrate buffer.
Background	This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
Gene Symbol	TNF
Locus ID	7124

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