Human CD130 (GP130) ELISA Kit, 1 x 48-well (pre-coated)
CNY 3060.00
货期*
6周
规格
| Cited in 1 publication. |
Specifications
| Product Data | |
| Description | Human CD130 (GP130) ELISA Kit, 1 x 48-well (pre-coated) |
| Size | 1 x 48 wells (pre-coated) |
| Format | 1 x 48-well (pre-coated) |
| Assay Type | Solid Phase Sandwich ELISA |
| Assay Length | 1h40min |
| Signal | Colorimetric |
| Curve Range | 56.25-1800 pg/ml |
| Sample Type | Serum, Plasma, Cell culture supernatant |
| Sample Volume | 100 µl |
| Specificity | Recognizes both natural and recombinant human soluble gp130 |
| Sensitivity | 15 pg/ml |
| Cross Reactivity | No cross reactivity with other human soluble receptors. No interference with neither soluble gp80 nor IL-6. |
| Interference | No significant interference observed with available related molecules. |
| Components | ELISA Kits include pre-coated strip plates, biotinylated secondary antibody, standards, controls (where applicable), buffers, streptavidin-HRP, TMB, stop reagents, and a detailed procedure. |
| Background | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014] |
| Gene Symbol | IL6ST |
| Locus ID | 3572 |
| Standard Curve |
Representative Standard Curve
|
Citations (1)
| The use of this Assay Kits has been cited in the following citations: |
|---|
|
Evolution of a Potential Hormone Antagonist following Gene Splicing during Primate Evolution
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PLoS ONE
,PubMed ID 23724068
[IL6ST]
|
Documents
| Product Manuals |
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