Aldosterone ELISA Kit

Specifications

Product Data
Description	Aldosterone ELISA Kit
Size	1 kit
Format	96-well strip plate
Assay Type	Solid Phase Sandwich ELISA
Assay Length	3 hour
Signal	Colorimetric
Sample Type	Cell culture supernatant, serum, plasma
Sample Volume	10 ul
Specificity	Natural and recombinant human Aldosterone
Reactivity	Human
Interference	No significant interference observed with available related molecules.
Components	See the product information for more details
Background	The steroid hormone aldosterone is a potent mineral corticoid that is produced by the zona glomerulosa of the adrenal cortex in the adrenal gland. The synthesis and release are controlled by the renin-angiotensin-aldosterone system (RAAS)1, as well as by plasma potassium concentration 2, the pituitary peptide ACTH, and by the blood pressure via pressure sensitive baroreceptors in the vessel walls of nearly all large arteries of the body 3. Aldosterone binds to mineralocorticoid receptors (MR) and triggers the transcription of hormone-responsive genes. In consequence, aldosterone increases the blood pressure by reabsorption of sodium and water from the distal tubules of the kidney into the blood, secretion of potassium into the urine, and elevation of circulating blood volume.

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