Calcitonin (CALCA) Mouse Monoclonal Antibody [Clone ID: UMAB303]

Specifications

Product Data
Clone Name	UMAB303
Applications	IHC
Recommend Dilution	IHC 1:10000
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human Calcitonin(CALCA) (NP_001732). The exact sequence is proprietary.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Concentration	1mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Predicted Protein Size	15.5 kDa
Gene Name	calcitonin related polypeptide alpha
Database Link	NP_001732 Entrez Gene 796 Human UniProt ID P01258
Background	This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2014]
Synonyms	CALC1; CGRP; CGRP-alpha; CGRP-I; CGRP1; CT; KC; PCT
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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