SERPINB4 Mouse Monoclonal Antibody [Clone ID: UMAB16]

Specifications

Product Data
Clone Name	UMAB16
Applications	10k-ChIP, IF, IHC, WB
Recommend Dilution	WB 1:500, IHC 1:150, IF 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human SERPINB4 (NP_002965) produced in HEK293T cell.
Isotype	IgG1
Formulation	Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)
Reconstitution Method	For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific)
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	44.7 kDa
Gene Name	serpin family B member 4
Database Link	NP_002965 Entrez Gene 6318 Human UniProt ID P48594
Background	SERPINB4 is also called squamous cell carcinoma antigen 2 (SCCA-2) or leupin. It directly inhibits human granzyme proteolytic activity and that overexpression of SERPINB4 in HeLa cells inhibits recombinant granzyme-induced as well as NK cell-mediated cell death.
Synonyms	LEUPIN; PI11; SCCA-2; SCCA1; SCCA2
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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