PMS2 Rabbit Polyclonal Antibody
CAT＃: TA899002S
PMS2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 870.00
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CNY 300.00
CNY 1430.00
CNY 2900.00
CNY 6650.00
CNY 3080.00
Specifications
| Product Data | |
| Applications | ELISA, WB |
| Recommend Dilution | ELISA 1:5000-10000, WB 1:500 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | This antibody is raised against a recombinant protein of PMS2 expressed in HEK293 cells |
| Isotype | IgG |
| Formulation | Tissue culture buffer containing 1% BSA and 0.02% Sodium azide |
| Concentration | Lot dependent; please refer to CoA along with shipment |
| Purification | Purified from the immunized serum by affinity chromatography (Protein A/G) |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 95.8 kDa |
| Gene Name | PMS1 homolog 2, mismatch repair system component |
| Database Link | |
| Background | This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2008] |
| Synonyms | HNPCC4; MLH4; MMRCS4; PMS2CL; PMSL2 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Mismatch repair |
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