UBE2L3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~2000
Reactivity	Human, Rat, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human UBE2L3
Isotype	IgG
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	1.45 mg/ml
Purification	Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	17.7 kDa
Gene Name	ubiquitin conjugating enzyme E2 L3
Database Link	NP_003338 Entrez Gene 22195 MouseEntrez Gene 363836 RatEntrez Gene 7332 Human UniProt ID P68036
Background	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
Synonyms	E2-F1; L-UBC; UBCH7; UbcM4
Reference Data
Protein Pathways	Parkinson's disease, Ubiquitin mediated proteolysis

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