Dicer (DICER1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500~2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human DICER1
Isotype	IgG
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	1.19 mg/ml
Purification	Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	218.5 kDa
Gene Name	dicer 1, ribonuclease III
Database Link	NP_803187 Entrez Gene 192119 MouseEntrez Gene 299284 RatEntrez Gene 23405 Human UniProt ID Q9UPY3
Background	This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010]
Synonyms	DCR1; Dicer; Dicer1e; HERNA; K12H4.8-LIKE; MNG1; RMSE2
Reference Data
Protein Families	Druggable Genome

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