CCL27 Rabbit Polyclonal Antibody (Biotin conjugated)

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein of human CCL27
Isotype	IgG
Formulation	PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration	0.5 mg/ml
Purification	Purified from the immunized serum by affinity chromatography (Protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	12.62 kDa
Gene Name	C-C motif chemokine ligand 27
Database Link	NP_006655 Entrez Gene 10850 Human UniProt ID Q9Y4X3
Background	This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]
Synonyms	ALP; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Chemokine signaling pathway, Cytokine-cytokine receptor interaction

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