BCMA (TNFRSF17) Mouse Monoclonal Antibody [Clone ID: OTI11B1]

Specifications

Product Data
Clone Name	OTI11B1
Applications	FC
Recommend Dilution	FC 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Recombinant full length protein of human TNFRSF17/BCMA (NP_001183) produced in HEK293 cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	20.1 kDa
Gene Name	tumor necrosis factor receptor superfamily member 17
Database Link	NP_001183 Entrez Gene 608 Human UniProt ID Q02223
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Synonyms	BCM; BCMA; CD269; TNFRSF13A
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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