MICB Mouse Monoclonal Antibody [Clone ID: OTI4C8]

Specifications

Product Data
Clone Name	OTI4C8
Applications	FC
Recommend Dilution	FLOW 1:100
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 23-309 of human MICB (NP_005922) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Shipped at -20°C or with ice packs, Upon delivery store at -20°C. Dilute in PBS(pH7.3) if necessary. Stable for 12 months from date of receipt. Avoid repeated freeze-thaws.
Predicted Protein Size	42.4 kDa
Gene Name	MHC class I polypeptide-related sequence B
Database Link	NP_005922 Entrez Gene 4277 Human UniProt ID Q29980
Background	This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Synonyms	PERB11.2
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Natural killer cell mediated cytotoxicity

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