YAP1 Mouse Monoclonal Antibody [Clone ID: OTI5E6]

Specifications

Product Data
Clone Name	OTI5E6
Applications	WB
Recommend Dilution	WB 1:1000
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 347-504 of human YAP1 (NP_001123617) produced in E.coli.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	54.3 kDa
Database Link	NP_001123617 Entrez Gene 22601 Mouse
Background	This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]
Synonyms	COB1; YAP; YAP2; YAP65; YKI
Reference Data
Protein Families	Druggable Genome

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