Complement C4B (C4B) Mouse Monoclonal Antibody [Clone ID: OTI1B2]

Specifications

Product Data
Clone Name	OTI1B2
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 1100-1350 of human C4B (NP_001002029) produced in E.coli.
Isotype	IgG2a
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	complement component 4B (Chido blood group)
Database Link	NP_001002029 Entrez Gene 721 Human UniProt ID P0C0L5
Background	Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. [UniProtKB/Swiss-Prot Function]
Synonyms	C4B1; C4B2; C4B3; C4B5; C4B12; C4BD; C4B_2; C4F; CH; CO4; CPAMD3
Reference Data
Protein Pathways	Complement and coagulation cascades, Systemic lupus erythematosus

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