RACGAP1 Mouse Monoclonal Antibody [Clone ID: OTI3A5]

Specifications

Product Data
Clone Name	OTI3A5
Applications	IHC, WB
Recommend Dilution	WB 1:500~2000, IHC 1:2000
Reactivity	Human, Monkey, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 123-238 of human RACGAP1 (NP_001119575) produced in E.coli.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	Rac GTPase activating protein 1
Database Link	NP_001119575 Entrez Gene 26934 MouseEntrez Gene 315298 RatEntrez Gene 711887 MonkeyEntrez Gene 29127 Human UniProt ID Q9H0H5
Background	This gene encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. This protein plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for this gene. There is a pseudogene for this gene on chromosome 12. [provided by RefSeq, Feb 2016]
Synonyms	CYK4; HsCYK-4; ID-GAP; MgcRacGAP
Reference Data
Protein Families	Druggable Genome

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