Dnmt2 (TRDMT1) Mouse Monoclonal Antibody [Clone ID: OTI8H10]

Specifications

Product Data
Clone Name	OTI8H10
Applications	WB
Recommend Dilution	WB 1:500~2000
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 84-293 of human TRDMT1 (NP_004403) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	44.4 kDa
Gene Name	tRNA aspartic acid methyltransferase 1
Database Link	NP_004403 Entrez Gene 13434 MouseEntrez Gene 1787 Human UniProt ID O14717
Background	This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]
Synonyms	DMNT2; DNMT2; MHSAIIP; PUMET; RNMT1
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Cysteine and methionine metabolism, Metabolic pathways

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