TBX3 Mouse Monoclonal Antibody [Clone ID: OTI8H5]

Specifications

Product Data
Clone Name	OTI8H5
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 244-481 of human TBX3 (NP_057653) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	79.2 kDa
Gene Name	T-box 3
Database Link	NP_057653 Entrez Gene 21386 MouseEntrez Gene 353305 RatEntrez Gene 6926 Human UniProt ID O15119
Background	This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms; however, the full length nature of one variant has not been determined. [provided by RefSeq, Jul 2008]
Synonyms	TBX3-ISO; UMS; XHL
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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