RUNX3 Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2G1]

Specifications

Product Data
Clone Name	OTI2G1
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:500
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human RUNX3 (NP_001026850) produced in E.coli.
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Gene Name	runt related transcription factor 3
Database Link	NP_001026850 Entrez Gene 12399 MouseEntrez Gene 156726 RatEntrez Gene 864 Human UniProt ID Q13761
Background	This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms	AML2; CBFA3; PEBP2aC
Reference Data
Protein Families	Transcription Factors

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