LZTS1 Mouse Monoclonal Antibody [Clone ID: OTI3D12]

Specifications

Product Data
Clone Name	OTI3D12
Applications	WB
Recommend Dilution	WB 1:500~2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human LZTS1 (NP_066300) produced in HEK293T Cell.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	66.4 kDa
Gene Name	leucine zipper, putative tumor suppressor 1
Database Link	NP_066300 Entrez Gene 211134 MouseEntrez Gene 266711 RatEntrez Gene 11178 Human UniProt ID Q9Y250
Background	This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer. [provided by RefSeq, Nov 2009]
Synonyms	F37; FEZ1
Reference Data
Protein Families	Druggable Genome

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