n-Myc (MYCN) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI2E5]

Specifications

Product Data
Clone Name	OTI2E5
Applications	WB
Recommend Dilution	WB 1:500
Reactivity	Human, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 229-464 of human MYCN(NP_005369) produced in E.coli.
Isotype	IgG1
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	49.4 kDa
Gene Name	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
Database Link	NP_005369 Entrez Gene 4613 Human UniProt ID P04198
Background	This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
Synonyms	bHLHe37; MODED; N-myc; NMYC; ODED
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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