COPS3 Mouse Monoclonal Antibody [Clone ID: OTI3E1]

Specifications

Product Data
Clone Name	OTI3E1
Applications	WB
Recommend Dilution	WB 1:2000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Human recombinant protein fragment corresponding to amino acids 224-423 of human COPS3(NP_003644) produced in E.coli.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	1 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	COP9 signalosome subunit 3
Database Link	NP_003644 Entrez Gene 26572 MouseEntrez Gene 287367 RatEntrez Gene 8533 Human UniProt ID Q9UNS2
Background	The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Synonyms	CSN3; SGN3
Reference Data
Protein Families	Stem cell - Pluripotency

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