MAD4 (MXD4) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI7F7]

Specifications

Product Data
Clone Name	OTI7F7
Applications	IHC, WB
Recommend Dilution	WB 1:2000, IHC 1:150
Reactivity	Human, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Full length human recombinant protein of human MXD4(NP_006445) produced in E.coli.
Isotype	IgG2b
Formulation	PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration	0.5 mg/ml
Purification	Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
Conjugation	Biotin
Storage Condition	Store at -20°C as received.
Predicted Protein Size	23.3 kDa
Gene Name	MAX dimerization protein 4
Database Link	NP_006445 Entrez Gene 17122 MouseEntrez Gene 10608 Human UniProt ID Q14582
Background	This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]
Synonyms	bHLHc12; MAD4; MST149; MSTP149
Reference Data
Protein Families	Druggable Genome, Transcription Factors

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